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Anthropometric parameters of idiopathic familial short stature females and its correlation with height and comparison with the control group
Karishma Sharma1, Rishita Chandra2, Brijendra Singh1, Shashi Ranjan Mani Yadav3, Manisha Naithani3, Surekha Kishore4, Vivek Mishra5, Kriti Mohan6, Prashant Kumar Verma7
1 Department of Anatomy, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
2 Department of MPH, All India Institute of Medical Sciences, Rishikesh, Uttarakhand; Project Manager-MIS, PHRS Department of Community and Family Medicine, Odisha, India
3 Department of Biochemistry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
4 Department of Community and Family Medicine, AIIMS, Gorakhpur, Uttarakhand, India
5 Department of Anatomy, AIIMS, Gorakhpur, Uttarakhand, India
6 Department of Paediatrics, AIIMS, Gorakhpur, Uttarakhand, India
7 Department of Paediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Correspondence Address:
Dr. Prashant Kumar Verma
Department of Paediatrics, All India Institute of Medical Sciences, Rishikesh - 249 203, Uttarakhand
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jasi.jasi_182_21
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Introduction: Familial Short stature is considered one of the most common causes of Short Stature along with the constitutional delay in growth and puberty (CDGP) from which it can easily be distinguish. The core parameters of anthropometry represent diagnostic criteria for obesity and other non-communicable diseases. To measure the anthropometric parameters in the patients with idiopathic clinically non-syndromic familial short-stature and to correlate those parameters with their height and compare them with the control group. Material and Methods: A cross-sectional study was conducted among Familial Short Stature females of 5-18 years age group referred from Paediatric and Genetic OPD of AIIMS, Rishkesh. Non-parametric tests were applied for comparing the variables and correlation coefficients were obtained. Results: There was a significant difference between the groups in terms of Standing Height (cm) (W = 376.000, P = <0.001), BMI (Kg/m2) (W = 1128.500, P = 0.002), with the median BMI (Kg/m2) and Waist/Height Ratio (W = 1164.500, P = <0.001), with the median Waist/Height Ratio being highest in the Short-Stature group. There was moderate to strong positive correlation between standing height and other anthropometric parameters. The mean waist to height ratio of 0.6 among short stature and 0.5 among the control group, with short stature having more odds of getting overweight and also shows a greater predilection of short-stature group for developing Cardio-vascular diseases. Discussion and Conclusion: Familial short stature though being a manifestation of some underlying cause, can fall in a non-syndromic group until further studies including karyotyping, next-generation sequencing etc. Extensive research for appropriate categorization and how this can effectively help combat the burden of malnutrition and non-communicable diseases should be done.
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